Overall, results obtained by Nciki et al. The reduction in faecal egg counts in dosed extracts with E. elephantina against mixed gastrointestinal parasite infections shows that this species possess anthelmintic properties and there is credence in its ethnoveterinary use against gastrointestinal parasites in goats. Elephantorrhiza elephantina is usually widespread, often gregarious and forming huge patches in … Elephantorrhiza elephantina (Ee) ... A little powder of plant specimen was mixed with Kbr salt using a mortar and pestle, and compressed into thin pellets. Although E. elephantina is widely used as traditional remedy for fever in Mozambique , South Africa , and Zimbabwe , the species did not display promising in vitro antiplasmodial activity, to support its traditional usage in the management and treatment of fever. According to Semenya et al. Ex. By utilising our research and development capabilities, we also ventured into Active Pharmaceutical Ingredient (API) development and supporting API master files. Kuntze ex Thell (UNIN 12298) were collected in April 2015 at University of Limpopo, South Africa. There was complete recovery within one week of treatment. Mimosaceae, Mimosengewächse, Fam.  revealed that E. elephantina root decoction is taken orally in combination with Cladostemon kirkii (Oliv.) Elephantorrhiza elephantina is mainly used to treat disorders of the gastrointestinal tract (21 citations in six countries), followed by veterinary medicine (14 citations in two countries), skin diseases (six citations from South Africa only), pain (five citations in five countries), and infertility and impotence (five citations in four countries). The synergistic interactions noted for Pentanisia prunelloides and E. elephantina by Mabona et al. The fruit is a compressed-oblong, straight or slightly curved pod 5–21 cm long and 3–6 cm wide, red-brown in colour, prominently transversely veined, and often swollen over the seeds . Anthocyanidins, anthraquinones, esters, fatty acids, phenolic compounds, flavonoids, glycosides, polysterols, saponins, sugars, tannins, and triterpenoids have been demonstrated to be the main active ingredients of E. elephantina.  isolated kaempferol 2, epicatechin 14, glucuronic acid 42, arabinose 43, epigallocatechin gallate 44, quercetin 45, and epicatechin gallate 46. B. Hansen (bark), and Ranunculus multifidus Forssk. Elephantorrhiza elephantina (Burch.) Tambo district, Eastern Cape Province, South Africa,”, S. O. Bandeira, F. Gaspar, and F. P. Pagula, “African ethnobotany and healthcare: emphasis on Mozambique,”, S. S. Semenya and M. J. Potgieter, “Ethnobotanical survey of medicinal plants used by Bapedi traditional healers to treat erectile dysfunction in the Limpopo Province, South Africa,”, S. S. Semenya, M. J. Potgieter, and L. J. C. Erasmus, “Ethnobotanical survey of medicinal plants used by Bapedi healers to treat diabetes mellitus in the Limpopo Province, South Africa,”, S. Nciki, S. Vuuren, A. van Eyk, and H. de Wet, “Plants used to treat skin diseases in northern Maputaland, South Africa: antimicrobial activity and in vitro permeability studies,”, H. de Wet, S. Nciki, and S. F. van Vuuren, “Medicinal plants used for the treatment of various skin disorders by a rural community in northern Maputaland, South Africa,”, D. van der Merwe, G. E. Swan, and C. J. Botha, “Use of ethnoveterinary medicinal plants in cattle by Setswana-speaking people in the Madikwe area of the North West Province of South Africa,”, A. P. Dold and M. L. Cocks, “Traditional veterinary medicine in the Alice district of the Eastern Cape Province, South Africa,”, S. J. Mpofu, T. A. M. Msagati, and R. W. M. Krause, “Cytotoxicity, phytochemical analysis and antioxidant activity of crude extracts from rhizomes of, H. Z. Msimanga, J. Fenstermacher, A. Levitz, I. Najimudeen, C. Phillips, and E. M. Wysocki, “Identification of compounds in hexane extracts of, S. J. Mpofu, T. A. M. Msagati, and R. W. M. Krause, “Flavonoids from the rhizomes of, V. Maphosa, P. J. Masika, E. S. Bizimenyera, and J. N. Eloff, “, V. Maphosa and P. J. Masika, “Anthelmintic screening of fractions of, U. Mabona, A. Viljoen, E. Shikanga, A. Marston, and S. van Vuuren, “Antimicrobial activity of southern African medicinal plants with dermatological relevance: from an ethnopharmacological screening approach, to combination studies and the isolation of a bioactive compound,”, V. Maphosa, P. J. Masika, and B. Moyo, “Investigation of the anti-inflammatory and antinociceptive activities of, C. Clarkson, V. J. Maharaj, N. R. Crouch et al., “In vitro antiplasmodial activity of medicinal plants native to or naturalised in South Africa,”, V. Naidoo, E. Zweygarth, J. N. Eloff, and G. E. Swan, “Identification of anti-babesial activity for four ethnoveterinary plants in vitro,”, V. Naidoo, E. Zweygarth, and G. E. Swan, “Determination and quantification of the in vitro activity of, C. Cueva, S. Mingo, I. Muñoz-González et al., “Antibacterial activity of wine phenolic compounds and oenological extracts against potential respiratory pathogens,”, F. A. Hashem and M. M. Saleh, “Antimicrobial components of some cruciferae plants (, J. Yang, X. Hou, P. S. Mir, and T. A. McAllister, “Anti-Escherichia coli O157:H7 activity of free fatty acids under varying pH,”, M. Abhilash, “In silico analysis of cranberry proanthocyanidin epicatechin (4beta-8, 2beta-0-7) as an inhibitor for modelled afimbrial adhesin virulence protein of uropathogenic, R. Krause, E. Schwab, D. Bachhiesl et al., “Role of, A. Jouret-Mourin and K. Geboes, “Infectious colitis,”, N. P. Mishchenko, S. A. Fedoreev, V. M. Bryukhanov et al., “Chemical composition and pharmacological activity of anthraquinones from, J. D. Phillipson, C. W. Wright, G. C. Kirby, and D. C. Warhurst, “Tropical plants as sources of antiprotozoal agents,” in, A. R. Ndhlala, C. Mupure, K. Chitindingu et al., “Antioxidant potentials and degrees of polymerization of six wild fruits,”, T. Kalaivani, C. Rajasekaran, and L. Mathew, “Free radical scavenging, cytotoxic, and hemolytic activities of an active antioxidant compound ethyl gallate from leaves of Acacia Nilotica(L.) wild. Copyright © 2017 Alfred Maroyi. A total of 42 and 14 human and animal ailments and diseases, respectively, are treated by herbal medicines prepared from E. elephantina (Table 2). Fabaceae ) were selected in this study also revealed efficacy of E. elephantina extract was administered (... 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